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What is a creatinine clearance??


Answers: The creatinine clearance test compares the level of creatinine in urine with the creatinine level in the blood, usually based on measurements of a 24-hour urine sample and a blood sample drawn at the end of the 24-hour period. Clearance is often measured as milliliters/minute (ml/min).

Because creatinine is found in stable plasma concentrations, is freely filtered and not reabsorbed, and is minimally secreted by the kidneys, creatinine clearance is used to estimate the glomerular filtration rate (GFR). The GFR in turn is the standard by which kidney function is assessed.

A 24-hour urine sample generally required. Occasionally, 6- or 12-hour urine collections can be done alternatively. The health care provider will instruct you, if necessary, to discontinue drugs that may interfere with the test.

On day 1, urinate into the toilet when you get up in the morning.
Afterwards, collect all urine in a special container for the next 24 hours.
On day 2, urinate into the container when you get up in the morning.
Cap the container. Keep it in the refrigerator or a cool place during the collection period. Label the container with your name, the date, the time of completion, and return it as instructed.
A measurement of the serum creatinine level is often used to evaluate kidney function. Urine creatinine levels can be used as a screening test to evaluate kidney function, or can be part of the creatinine clearance test.


The creatinine clearance test compares the level of creatinine in urine with the creatinine level in the blood, usually based on measurements of a 24-hour urine sample and a blood sample drawn at the end of the 24-hour period. Clearance is often measured as milliliters/minute (ml/min).

Because creatinine is found in stable plasma concentrations, is freely filtered and not reabsorbed, and is minimally secreted by the kidneys, creatinine clearance is used to estimate the glomerular filtration rate (GFR) -- the standard by which kidney function is assessed.
It's a test to judge the level of kidney function. Creatinine is a breakdown product from muscle use that is always circulating in the bloodstream. The amount which your kidneys can get rid of in a day shows how well they are functioning.


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